Hereditary nonpolyposis colorectal cancer (HNPCC) is subdivided into Lynch syndrome I (site-specific colonic cancer) and Lynch syndrome II (extracolonic cancer), particularly carcinoma of the stomach, endometrium, biliary and pancreatic system, and urinary tract. HNPCC disorders show a proclivity to early onset, predominant proximal location of colon cancer and a dominant pattern of inheritance (for more details see 120435).
• Informasjon om indikasjonen (GeneReviews)
• Informasjon om indikasjonen (OMIM nr.: #120435)